Do you want to know how CBD affects your body and can it build a tolerance? Hello everyone in this article I am going to talk about CBD tolerance, its uses, doses, side effects, and much more. Many of the drugs and substances like caffeine can develop tolerance in yourself. That’s why many of the people have a question in their mind “can you build a tolerance to CBD?”.

Before talking about CBD tolerance, let’s talk about Tolerance and what does tolerance means. For example, if someone is taking two and more cups of coffee a day, then think backs to when he started. It’s likely that he began one cup a day, but over time one cup becomes less effective for him to keep going. That’s why he has to take more and more, and in this way, your body builds up a tolerance to caffeine.

There are so many benefits of CBD, people are using it for general wellness and two more therapeutic purposes. People also claim that it helps in relaxation as well as in pain killers. Many people are using CBD for getting relief from anxiety and depression.

Can I Build up a Tolerance to CBD?

Many People ask is this possible for people to build up a tolerance to their medical cannabis medication? The answer is both yes and no because the tolerance profile for both CBD and THC are different. THC and CBD both are found in the cannabis plant and it is observed that regular THC users lead to a higher tolerance to THC but it is not true for CBD because it can build a tolerance in yourself.

In the case of CBD, it’s totally false because CBD and THC don’t affect to CB1 receptors in the same way. That’s why it does not seem to build a tolerance to CBD oil in regular users.

According to recent research on CBD can you build tolerance, it is observed that regular users of CBD do not cause tolerance to CBD over time. In fact, after observing consistent CBD user’s reports, it is noticed that at that time they have to take a less amount of CBD to achieve the same results, this is called reverse tolerance.

What is reverse tolerance? Well, the answer is many of antidepressants or antibiotics are prescribed on higher doses initially to combat the illness. But after some time the patient can move too much lower doses to maintain or to achieve the same results, this phenomenon is known as reverse tolerance. This phenomenon is the same for CBD, after higher doses it increasing the sensitivity of cannabinoid receptors and the endocannabinoid system.

That’s why after a few weeks you can move to lower doses of CBD to achieve the same benefits of CBD oil and this is known as reverse tolerance. But if you are not getting any desired effects, take a tolerance break for a week. In reverse tolerance you can start taking CBD at a lower dose to achieve the results at that time, this type of doses know as maintenance does.

How Long Does CBD Stay In Our System?

Generally, CBD stays 3 to 5 days in our endocannabinoid system and affects our cannabinoid receptors and it does not cause tolerance, but in some cases, it may differ, maybe a week. How long it stays in our system depends on the following factors.

  1. How much you have taken
  2. In what intervals you have used CBD
  3. Your Body
  4. Food In Your stomach

1. How Much You Have Taken

The first factor is how much you have taken, if you use the higher dose then it will stay more in the system.

2. In What Intervals You Have Used CBD

The second most important factor is in how many intervals you have consumed CBD. If you will use it more frequently, then it will show a long-lasting effect on your body. At the initial stage, people can’t get CBD’s effects, that’s why its initial doses are high and doctors recommend patients to use CBD at least for a week to see its effects.

3. Your Body

Everyone’s body is different, that’s why every medicine, drug, and treatment and can cure or prevent any disease. Tolerance to CBD or other drug’s effect may differ from person to person because everyone’s metabolism, weight, and mass index is different.

4. Food In Your stomach

It is also a factor that decides how much longer it stays in our system because if your stomach is full and if have taken CBD then it will take at least 2 hours to show its effect. Because if you use CBD oil when your stomach is full then your body firstly digests food in the stomach and then will process CBD. And if your stomach is clean, then it will directly start digesting CBD oil, and it will take only 15 to 30 minutes to show its effect.

Can You Become Reliant On CBD?

According to a survey, 26% of American people have used CBD oil in the past two years. And scientific research shows that CBD is very much safe from THC and other cannabinoids. Many people think that CBD and THC both are the same and can affect our bodies in a bad manner. But I want to inform you that they both are different.

As compared with THC, effects of CBD does not affect psychological functions like blood pressure, body temperature, and heart rate. So THC can be addictive but CBD generally can not, but it depends on where the CBD comes from because many of the CBD products are varying levels of THC.

Can you have a bad reaction to CBD?

According to a study on CBD oil in 2017 told us that it is very much safe as compared to THC and other drugs. As I told above THC is a psychoactive compound that is responsible for most of the physiological effects but CBD works differently. It is not psychoactive in nature and can be used in various types of treatments. That’s why the Food and Drug Administration (FDA) has approved drugs, which contain CBD and intended to diagnose treatments.

That’s why the World Health Organization (WHO) finds no public health risk or abuse potential for CBD oil. According to WHO’s report in 2018 shows that natural use of CBD oil is fully safe and well-tolerated in humans. They also highlighted that CBD oil is not associated with any negative public health effects.


In final words, if you are thinking to use CBD oil for any health purposes or treatment, then you can use it. Because it has no side effects and it can not build any tolerance in you for CBD. In fact, the World Health Organization (WHO) and the Food and Drug Administration (FDA) approved it. They also highlighted that it is fully safe to use CBD oil in humans and animals, and it does not have bad side effects. SO if you have any questions in your mind related to CBD oil, then please let us know in the comment section.